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    Biosharp产品助力科研,代表性文献分享

    2020-11-30

    2020614日, 南京农业大学的研究团队在《Antioxidant》发表了题为“Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway”的研究成果。研究人员发现游离脂肪酸诱导的活性氧可以通过Nrf2/p53信号通路介导颗粒细胞的凋亡。这项研究表明游离脂肪酸的量会直接影响原代培养颗粒细胞的凋亡,活性氧在其中起到了非常重要的作用。这些发现进一步揭示了颗粒细胞的凋亡机制,对提升卵巢功能具有潜在意义。

    在该研究中使用了Biosharp 的二抗和ECL检测试剂盒。

    相关产品:

    产品编号

    产品名称

    规格

    BL520A

    ECL化学发光底物(特超敏)

    100ml

    BL520B

    ECL化学发光底物(特超敏)

    500ml

    BL523A

    ECL化学发光底物(超敏)

    100ml

    BL523B

    ECL化学发光底物(超敏)

    500ml

    BL001A

    BL001A 羊抗小鼠IgG-HRP

    0.1ml

    BL002A

    BL002A 羊抗大鼠IgG-HRP

    0.1ml

    BL003A

    BL003A 羊抗兔IgG-HRP

    0.1ml

    BL004A

    BL004A 兔抗羊IgG-HRP

    0.1ml

    其他使用该产品的部分文献摘录:

    1.      Wang Y, Li C, Li J, et al. Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway[J]. Antioxidants, 2020, 9(6): 523.   IF: 5.014

    2.      Shah S W A, Chen J, Han Q, et al. Ammonia inhalation impaired immune function and mitochondrial integrity in the broilers bursa of fabricius: Implication of oxidative stress and apoptosis[J]. Ecotoxicology and environmental safety, 2020, 190: 110078.   IF: 4.872

    3.      Wang Y, Yang C, Hassan N A. HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress[J]. Aging (Albany Ny), 2019, 11(15): 5535.   IF: 4.831

    4.      Yu C, Ding B, Zhang X, et al. Targeted iron nanoparticles with platinum-(IV) prodrugs and anti-EZH2 siRNA show great synergy in combating drug resistance in vitro and in vivo[J]. Biomaterials, 2018, 155: 112-123.  IF: 10.317

    5.      Wang L L, Yu Q L, Han L, et al. Study on the effect of reactive oxygen species-mediated oxidative stress on the activation of mitochondrial apoptosis and the tenderness of yak meat[J]. Food chemistry, 2018, 244: 394-402.    IF: 5.399

    2019329日, 南京医科大学附属第一医院的研究团队在《Journal of cellular physiology》发表了题为“Protective effects of microRNA-22-3p against retinal pigment epithelial inflammatory damage by targeting NLRP3 inflammasome”的研究成果。研究人员发现了microRNA-22-3p在视网膜色素上皮炎性损伤中发挥的作用。其研究结果表明microRNA-22-3p通过NLRP3炎性体可以有效抑制视网膜色素上皮炎性损伤,为未来视网膜病的介入治疗提供了新的思路。

    在该研究中使用了Biosharp CCK-8试剂盒检测了ARPE‐19细胞的细胞活性。

    相关产品:

    产品编号

    产品名称

    规格

    BS350A

    CCK-8 细胞增殖-毒性检测试剂盒

    100 孔,1 ml

    BS350B

    CCK-8 细胞增殖-毒性检测试剂盒

    500 孔,5×1 ml

    其他使用该产品的部分文献摘录:

    1.      Wei R, Mao L, Xu P, et al. Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models[J]. Food & function, 2018, 9(11): 5682-5696.     IF: 4.171

    2.      Yuan J, Chen H, Ge D, et al. Mir-21 promotes cardiac fibrosis after myocardial infarction via targeting Smad7[J]. Cellular Physiology and Biochemistry, 2017, 42(6): 2207-2219.  IF: 5.5

    3.      Zhang J, Song X, Cao W, et al. Autophagy and mitochondrial dysfunction in adjuvant-arthritis rats treatment with resveratrol[J]. Scientific reports, 2016, 6: 32928.  IF: 4.259

    4.      Liu H, Liu J, Qi C, et al. Thermosensitive injectable in-situ forming carboxymethyl chitin hydrogel for three-dimensional cell culture[J]. Acta biomaterialia, 2016, 35: 228-237.   IF: 6.319

    2019410日, 上海交通大学医学院的研究团队在《Journal of cellular physiology》发表了题为“LY411575, a potent γ‐secretase inhibitor, suppresses osteoclastogenesis in vitro and LPS‐induced calvarial osteolysis in vivo”的研究成果。研究人员发现LY411575 作为一种分泌酶抑制剂,可以有效抑制破骨细胞分化,破骨细胞特异基因表达和骨吸收,这一过程是通过抑制Notch/HES1/MAPK (ERK and p38)/Akt 介导的NFATc1诱导实现的。这项研究为破骨细胞介导的溶骨性骨病的治疗方案提供了参考。

    在该研究中使用了Biosharp BCA蛋白浓度测定试剂盒。

    产品编号

    产品名称

    规格

    BL521A

    BCA蛋白浓度测定试剂盒

    500T

    其他使用该产品的部分文献摘录:

    1.      Xie L , Zhai R , Chen T , et al. Panax Notoginseng Ameliorates Podocyte EMT by Targeting the Wnt/β-Catenin Signaling Pathway in STZ-Induced Diabetic Rats[J]. Drug Design, Development and Therapy, 2020, Volume 14:527-538.    IF: 3.216

    2.      Jiang L, Liu T, Xie L, et al. AICAR prolongs corneal allograft survival via the AMPK-mTOR signaling pathway in mice[J]. Biomedicine & Pharmacotherapy, 2019, 113: 108558.     IF: 4.545

    3.      Lin Z, Zhao X, Huang J, et al. Rapid screening of colistin-resistant Escherichia coli, Acinetobacter baumannii and Pseudomonas aeruginosa by the use of Raman spectroscopy and hierarchical cluster analysis[J]. Analyst, 2019, 144(8): 2803-2810.     IF: 3.978

    4.      Yao L, Li H, Yang J, et al. Purification and characterization of a hydroxynitrile lyase from Amygdalus pedunculata Pall[J]. International journal of biological macromolecules, 2018, 118: 189-194.   IF: 5.162

    5.      Song F, Sun H, Wang Y, et al. Pannexin3 inhibits TNF‐α‐induced inflammatory response by suppressing NF‐κB signalling pathway in human dental pulp cells[J]. Journal of cellular and molecular medicine, 2017, 21(3): 444-455.   IF: 4.486